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Shingles is an infection caused by reactivation of the Varicella-zoster virus (VZV) that was hiding in the dorsal root ganglion after being infected.
Shingles is possibly spread from the occurrence of blisters to the encrusted lesions, and usually spread by direct contact with the lesion.
The rashes and blisters locally appear only on the side where the ganglia of the dorsal nerve root are located, and the affected area can be accompanied by severe pain and paraesthesia. Approximately 30% of older people have neuralgia, and may have Ramsay-Hunt syndrome, which is unusually accompanied by shingles and facial paralysis or vestibulocochlear nerve symptoms. Shingles is not common in children, but symptoms are minor even if occurred.
Vaccination can prevent the disease regardless of past infections.
The most common side effects are redness, pain, and edema.